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- 1st appearance of the "real" Domino (Copycat masquerades as Domino in New Mutants #98 and a flashback in X-Force #8)
- 1st team appearance of Weapon P.R.I.M.E. (Weapon X, Rictor, Yeti and Tygerstryke)
- 1st appearance of Pete Wisdom, a mutant who creates fiery knives from solar radiation
- A variant Deluxe Edition includes Fleer trading cards attached to binding (does not affect values)
- 1st team appearance of X-Statix (Battering Ram, Gin Genie, La Nuit, Plazm, Sluk, Zeitgeist, Doop and U-Go Girl)
- 1st appearance of Zeitgeist
- 1st appeaarance of Doop