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- 1st cameo team appearance of The Nine (Midnight Sons): Ghost Rider, Johnny Blaze, Morbius, Blade, Hannibal King, Frank Drake, Sam Buchanan, Victoria Montesi, Louise Hastings
- 1st appearance of the Caretaker
- *confirmed character to appear in the Helstrom series
- 1st appearance of Lilith
- 1st appearance of Meatmarket, offspring of Lilith