Howard Mackie

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  • First interior art by Amanda Conner
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  • 1st appearance of Nth Man
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  • 1st appearance of Daniel Ketch as the second Marvel Ghost Rider (possessed by Noble Kale)
  • 1st appearance of Deathwatch
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  • 1st appearance of Blackout, a vampire
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  • Reintroduction of Johnny Blaze
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  • 1st team-up of Moon Knight and Ghost Rider
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  • Debut of Johnny Blaze's hellfire shotgun
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  • 1st glow-in-the-dark comic cover
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  • 1st appearance of Michael Badilino (becomes Vengeance)
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  • 1st appearance of the Demogoblin, separated from Hobgoblin, Jason Macendale
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  • 2nd appearance and 1st cover appearance of Doppelganger Spider-Man
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  • Anniversary issue celebrating 30 years of Spider-Man
  • Double-page advertisement of Spider-Man 2099
  • 1st appearance of a Venom/Galactus character
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  • 1st cameo team appearance of The Nine (Midnight Sons): Ghost Rider, Johnny Blaze, Morbius, Blade, Hannibal King, Frank Drake, Sam Buchanan, Victoria Montesi, Louise Hastings
  • 1st appearance of the Caretaker
  • *confirmed character to appear in the Helstrom series
  • 1st appearance of Lilith
  • 1st appearance of Meatmarket, offspring of Lilith
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  • 1st full team appearance of the Midnight Sons
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  • Preview of Ravage 2099
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  • Preview of Doom 2099
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  • 1st appearance of Michael Badalino as Vengeance
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  • Variant cover art by Lee Weeks
  • Gold foil, embossed technique
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  • First title series featuring Gambit
  • Origin of Gambit
  • 1st appearance of Candra the Benefactoress
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  • 1st appearance of the Grim Hunter, son of Kraven the Hunter
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  • 1st appearance of Coldheart
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  • One-shot titled 'Dark Design'
  • Sequel to Ghost Rider, Wolverine, Punisher: Hearts of Darkness
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  • Symbiote tries to mimic Brock
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  • First solo series featuring Rogue
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  • Death of Ben Reilly
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  • 1st appearance of Loxias Crown, a vampire who later becomes known as The Hunger
  • *villain in the Morbius movie played by Matt Smith according to IMDb
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  • 1st appearance of Proto-Goblin, the test subject Norman injected with the Goblin Formula while trying to perfect it
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  • Debut of Spider-Man's Negative Zone suit, a black and white distortion of his traditional costume
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  • Debut of Spider-Man's Dusk costume and identity
  • *Peter assumed the role of four different aliases while evading capture for a false murder charge
  • *after Parker retired the four identities, a group of teenage superheroes each assumed one and collectively became known as The Slingers
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  • X-Factor disbands
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  • 1st appearance of Man-Spider, an alternate reality version of Spider-Man who had six arms
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  • 1st appearance of Hunger, formerly Crown
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  • 1st appearance of the third Spider-Woman, Mattie Franklin, in costume
  • 1st appearance of the fourth Spider-Woman, Charlotte Witter, the granddaughter of Madame Web
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  • 1st team appearance of the Exemplars
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  • Scarce, low print run
  • Cover art by Erik Larsen featuring Venom
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  • Scarce 100-page issue sporadically published by Marvel (one of nine 100-page monsters published in the early 2000s)
  • *newsstand versions exist but no sals data available
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  • Variant cover art by John Romita Jr. with foil
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  • Promotional giveaway sponsored by Doritos
  • Individually number from #1-#65,000
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  • Cover art by John Romita Jr. featuring Mary Jane
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  • Return of Vengeance, Michael Baldino