David Michelinie

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Iron Man #250

Marvel 1989 Vol. 1
Non-Key
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Iconic cover art by Todd McFarlane

Final artwork on the Amazing Spider-Man title by Todd McFarlane

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1st appearance of the Tri-Sentinel

Debut of Spider-Man’s Captain Universe suit

Spider-Man gains cosmic powers in The Spectacular Spider-Man #158

Amazing Spider-Man #329

Marvel 1990 Vol. 1
Non-Key
Newsstand
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First time Venom is depicted with a long tongue and drool, a significant addition to Venom's design, added by Erik Larsen

Hidden in the background of a panel featuring Spider-Man in a park are Charlie Brown and Snoopy having a picnic - tap cover and swipe to view additional image

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1st full team appearance of the Sinister Six II: Doctor Octopus, Electro, Mysterio, Sandman, Hobgoblin, Vulture

This is the second Sinister Six roster of villains

The Sinister Six introduced in The Amazing Spider-Man Annual #1 only appeared together once, therefore this issue would be the second full appearance ever of a Sinister Six team

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1st team appearance of the Femme Fatales: Knockout (1st), Mindblast (1st), Whiplash, Bloodlust

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1st appearance of Spider-Hulk

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1st appearance of Dr. Elias Wirtham, later revealed to be Cardiac

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1st cameo appearance of Cardiac

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1st appearance of Cletus Kasady, later becomes Carnage

1st full appearance of Cardiac, a doctor who vowed to find a cure for the ailment that caused the death of his brother

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Cletus Kasady becomes infected by the Venom symbiote, later becomes Carnage

[March 2026 - a glimpse of Spider-Man battling Boomerang in the Brand New Day trailer was inspired by this cover - tap cover and swipe to view screenshot]

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Iconic cover art by Erik Larsen

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Amazing Spider-Man #346

Marvel 1991 Vol. 1
Non-Key
International
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Amazing Spider-Man #346

Marvel 1991 Vol. 1
Non-Key
International
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Amazing Spider-Man #346

Marvel 1991 Vol. 1
Non-Key
International
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Amazing Spider-Man #346

Marvel 1991 Vol. 1
Non-Key
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Iconic cover art by Erik Larsen

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First solo story featuring Venom

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1st cameo appearance of Carnage, in one panel - a glob of red symbiote material can be seen

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Amazing Spider-Man #346

Marvel 1992 Vol. 1
Non-Key
UK Edition
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Rai #1

Valiant 1992 Vol. 1
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Scarce

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2nd cameo appearance of Carnage including mention by name, a hand, an arm and partial face

Toxic Crusaders #1

Marvel 1992 Vol. 1
Non-Key
Newsstand
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Rai #2

Valiant 1992 Vol. 1
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1st appearance of Icespike

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